A Revolution in Patient Safety

Sentire Medical Systems, LLC (Sentire) has developed and patented Perf-AlertTM, a revolutionary monitoring system that will alert surgeons to the presence of bowel perforations during laparoscopic surgical procedures. This revolution in patient safety enables immediate intraoperative repair protecting patients from one of the most devastating and costly risks of laparoscopic surgery. Perf-AlertTM is a non-invasive solution, elegant in its simplicity that will reduce readmissions, improve patient outcomes and dramatically reduce costs for payers and providers.


In the United States the mortality rate from undetected bowel perforation leading to sepsis exceeds 2,500 patients per year. The morbidity from the delay in treating bowel perforations can range from minor conditions to hypoxic brain injury and complete loss of cognitive function, colostomies, fistulas and many other complications.

When a bowel perforation occurs during laparoscopic surgery, many are not visualized or detected by the surgeon at the time of the event. In most cases, patients gradually develop symptoms related to the perforation and thus require an evaluation that involves a CT scan and an infectious disease assessment. When the perforation is identified intra-operatively, at the time of the occurrence, it can usually be repaired without complication. When the perforation is not visualized at the time of the incident, this usually necessitates an open laparotomy, with the patient having developed an abdominal infection, such as peritonitis or possibly sepsis - a condition which can lead to death.

Sentire was founded in 2011 and has been developing technology that will have a profound impact on patient safety and cost of care.

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